New Software Tool Enhances Genome-Sequencing

CoreDetector is a new software tool developed by researchers that improves genome-sequencing capabilities, allowing researchers to improve plants through breeding. CoreDetector is built to tackle computationally demanding tasks like matching big and evolutionary varied plant genomes. It uses computer parallelization to perform pairwise sequence alignment between the genomes of population members. The program supports diploid creatures such as humans and other animals. It may be applied to various species, from kilobyte bacteria genomes to gigabyte plant genomes such as wheat.

The software tool was also made available on GitHub, making it free and available to anybody who can profit from it. It will immediately impact plant pre-breeding and breeding studies, particularly for those working with more complicated plant genomes. The Java-based program is easily portable between operating systems and will allow rapid progress in genetic studies of varied populations. Open access to CoreDetector will continue to allow rapid improvement in genetic studies of various populations as high-throughput sequence technologies advance and more species can be sequenced.

It will provide plant breeders and researchers with an effective genome sequence analysis tool that can be used as part of an analytical pipeline to improve our genetic understanding of living organisms. The next generation of technology is being developed to expand CoreDetector’s theoretical and computational framework to get the core genome plus accessory sequences of a population, known as the pan-genome.

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