Detection of explosives (eg. in the field, baggage, or transit systems) has become an intense field of research over the last 15 years. Several physical (such as ion mobility spectrometry, mass spectrometry, and active neutron interrogation) and chemical (including calorimetry, fluorescence quenching, and electro-chemistry) techniques have been investigated as suitable detection mechanisms, and wide-ranging efforts [..]

Read More

A quantitative phase spectroscopy (QPS) system that incorporates digital holography has been used to spot malaria-infected cells from a simple, untouched blood sample without any help from a human. The technique employs machine learning algorithms and has been shown accurate in detecting malaria infection 97 to 100 percent of the time. The research could form [..]

Read More
Living Cells

Driven especially by advances in quantum cascade lasers (QCLs), infrared (IR) absorption spectroscopy has earned its stripes in recent years as a label-free technique for imaging a wide range of materials. Read more

Read More

A team of researchers at the University of Maryland (College Park, MD) and Harvard Medical School (Cambridge, MA) has developed a novel spectroscopy configuration that can obtain a biological sample’s entire Brillouin spectrum in one shot, saving time and allowing for noninvasive biological characterization in, say, potentially cancerous tumors. Read more

Read More

Techniques such as optical nanoscopy and spectroscopy have expanded our capability to probe biological cells at the nanoscale. These techniques provide the opportunity to learn about disease mechanisms at the cellular level, and therefore to improve disease detection and diagnosis. Now we have developed approaches for cellular biosensing that use optical information.. Read more

Read More

Limited availability of tests to diagnose cancer in its early stages has contributed to an unfortunate prevalence of late-stage diagnoses and metastatic spread. For this reason, emerging technologies that promise early diagnosis constitute a key focus of research. Mid-infrared imaging (MIR), with its ability to enable in vivo medical diagnosis, is particularly interesting. Read more

Read More

With certain cancers, such as ovarian cancers, a significant number of patients are non-responsive to the standard chemotherapy treatment. These patients, therefore, experience the negative side effects of chemotherapy without clinical benefits. With the ever-increasing number of available anti-cancer drug alternatives to chemotherapy…. Read more

Read More

Engineering researchers at Harvard University, USA, have devised an electromechanical approach to creating windows whose opacity can be tuned with the proverbial flick of a switch. The approach—which involves the electrostatic deformation of nanowire-coated elastomer layers—is color neutral, and could prove much cheaper to manufacture than previous, largely electrochemical techniques. Read more

Read More

A team of researchers turned to Raman spectroscopy to rapidly screen for and identify novel psychoactive substances (NPS), known commonly as “legal highs.” The approach will now enable statutory agencies to identify the actual substances contained within legal highs more quickly, thereby enabling more prompt public health messages to be issued out to communities. Read [..]

Read More

Using a portable device developed at Drexel University, researchers at Albert Einstein College of Medicine have identified differences in brain activation patterns associated with postural stability in people with Parkinsonian syndromes and healthy adults. Read more

Read More

A near-infrared (NIR) spectroscopy system has been used to measure cerebral changes and oxygen utilization in vivo, offering a noninvasive diagnostic technique for neonatal brain injury. The system used the Acton series LS-785 lens-based spectrograph and the PIXIS:512F scientific CCD camera from Princeton Instruments of Trenton, N.J. The camera’s cooling technology ensured low-noise performance. Read [..]

Read More

A team of researchers at Purdue University (West Lafayette, IN) has demonstrated that an In vivo spectroscopy technique can reveal the chemical composition of living tissue for medical diagnostics and cellular studies. Read more

Read More

Kidney stones are often no larger than a grain of rice, yet some can grow to measure several centimeters in diameter. Sometimes, a kidney stone might block the ureter, causing colic pain in the flank. If it cannot be dissolved, the kidney stone is treated using extracorporeal shock-wave therapy or by applying minimally invasive endoscopic [..]

Read More

Hyperspectral imaging (HSI) is a technique combining imaging and spectroscopy to survey a scene and extract detailed information. Also called imaging spectroscopy, HSI is a powerful, data-processing-intensive method that creates a “data cube” containing information about the properties of a target at hundreds to thousands of narrow wavelength bands within the system’s field of view. [..]

Read More

Single microresonators able to generate light pulses at several discrete frequencies could eliminate the need to integrate multiple lasers into communications and spectroscopy equipment. Researchers at Purdue University have developed a way use the microresonators as frequency combs, with precisely controlled emission at evenly spaced frequencies, using the concept of dark pulses. Read more here

Read More

A recent study has revealed that an IR frequency comb spectrometer could help clinicians detect diabetes, infections and cancer by analysing the air patients exhale. The researchers hope to have a working prototype in 2-3 years and a commercial product in 3-5 years. Read more here

Read More

A team of researchers has developed a new way to detect poor blood circulation using a novel way of Near Infra Red (NIR) spectroscopy. NIR spectroscopic 2D imaging can be used to monitor blood supply and circulation. Read more here

Read More