Open-Source Microscope Targets Brain Imaging And Disease Diagnosis

A team of researchers at Tel Aviv University in Israel has developed a new multiphoton microscopy tool, known as Pysight, for rapid 2D and 3D imaging of the brain and other tissues.

Among other things, the team hopes that the tool could soon boost scientists’ efforts to attain a deeper understand of brain dynamics, assisting in the discovery of groundbreaking treatments for a range of health problems including stroke, epilepsy and dementia.

Pablo Blinder, who heads up the team at the Neurobiology, Biochemistry and Biophysics School and Sagol School for Neuroscience at Tel Aviv University, explains that PySight combines commercially available, off-the-shelf hardware with open-source software tailored for photon-depleted imaging conditions, such as those characteristic of rapid multiphoton microscopy.

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