Non-Invasive Imaging Method Spots Cancer at the Molecular Level

Researchers for the first time have combined a powerful microscopy technique with automated image analysis algorithms to distinguish between healthy and metastatic cancerous tissue without relying on invasive biopsies or the use of a contrast dye.

This new approach could one day help doctors detect cancer metastasis that is otherwise difficult to see via standard imaging technologies during operations.

 

“Existing techniques are invaluable but suffer from low spatial resolution and often require the use of exogenous contrast agents,” said research team co-leader Thomas Schnelldorfer from Lahey Hospital, Burlington, Mass., U.S.A. “The method utilized in this work identifies in a completely label-free manner cellular and tissue features at the microscopic level, essentially acting like a biopsy without a knife,” added Dimitra Pouli from Tufts University, Medford, Mass., U.S.A., lead author of the study.

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