Because Helicobacter pylori infection is a considerable risk factor for stomach cancer, regular screening is essential. Endoscopic advancements have helped the removal of big neoplasms; however, finding faint epithelial neoplasms remains difficult. A study found that using LM-NBI (Narrow-Band Imaging At Low Magnification) for comprehensive stomach observation after routine white-light imaging (WLI) was effective, especially in regions exhibiting map-like redness or atrophic/metaplastic mucosa within the stomach. This group of lesions accounts for roughly one-quarter of all newly diagnosed minor neoplasms.
The goal was to assess the effectiveness of annual endoscopic examinations utilizing LM-NBI for the entire stomach following WLI to detect gastric neoplasms. The study discovered that among the 388 patients in the LM-NBI group and 381 in the CE group, 15 and five patients had gastric neoplasia, with one being a mucosa-associated lymphoid tissue lymphoma. All of the patients were diagnosed with epithelial neoplasia.
Endoscopic examinations were carried out successfully and without difficulties that necessitated extra treatments. The Cox proportional hazards model yielded a hazard ratio 2.78 (95% confidence interval, 1.01-7.64). According to a Kaplan-Meier study, annual LM-NBI outperformed CE in diagnosing gastric neoplasia. This historical case-control study shows that annual LM-NBI after WLI detects three times more neoplastic lesions in the stomach than CE. More research is needed to determine whether LM-NBI is preferable to other image-enhanced endoscopies, such as blue laser imaging brilliant and linked color imaging.
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