Scientists have developed the world’s first advanced laser microscope (laser scanning confocal microscope) that can use Circularly Polarized Light (CPL) to distinguish left and right-handed molecules, also known as chiral enantiomers, within live cells. This significant breakthrough will enable researchers to gain new insights into chiral molecules and analyze previously unexplored areas of biology and chemistry.
The CPL Laser Scanning Confocal Microscope (CPL-LSCM) is the first to track and distinguish left-handed molecules from right-handed molecules that can emit bright light, which was previously impossible.
When emitting light, left and right-handed molecules encode a unique optical fingerprint that contains information about the molecular environment, conformation, and binding state. Scientists worldwide will be able to study and examine this information for the first time using the novel microscope.
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