Scientists have invented the world’s first advanced laser microscope (laser scanning confocal microscope) that can harness Circularly Polarized Light (CPL) to differentiate left and right-handed molecules, also known as enantiomers of chiral molecules, within live cells. This discovery is a major breakthrough that will allow researchers to access new information on chiral molecules and analyze previously unexplored parts of biology and chemistry.
The microscope, known as CPL Laser Scanning Confocal Microscope (CPL-LSCM), is the first of its kind that can track and differentiate left-handed molecules from right-handed molecules that can emit bright light, which was not possible before.
The left and right-handed molecules encode a unique optical fingerprint when emitting light that contains information about the molecular environment, conformation, and binding state. For the first time ever, scientists around the world will be able to study and examine this information using the novel microscope.