DNA Computing With Microfluidic Chips

DNA computing uses the individual units of DNA’s two strands (selectively bound to each other in a complementary manner) to do complicated mathematical calculations. However, most DNA computing processes are still manual – one needs to add reactants step-by-step to the reaction. Finally, scientists have developed a programmable DNA-based microfluidic device that a personal computer can control, automating DNA calculations.

Scientists believe DNA-based CPUs will eventually replace electronic CPUs because they use less energy, which will help reduce global warming. The DNA-based CPUs can perform complex calculations, such as deep learning and mathematical modeling.

The chip has a motor-operated valve system controlled using a PC or smartphone. The chip and software together form a microfluidic processing unit (MPU). The MPU performs a series of reactions to execute a combination of logic operations rapidly and conveniently. Future research will focus on a total DNA computing solution with DNA algorithms and storage systems.

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