Traditionally, infrared (IR) spectroscopy has been a powerful tool for studying proteins. However, its application to single proteins has been limited due to the diffraction limit, which restricts the spatial resolution to hundreds of nanometers. This is far larger than the size of a typical protein, making it difficult to isolate and analyze individual molecules. [..]

Artificial intelligence (AI) is transforming microscopy by enhancing image efficiency and data analysis. A prominent example is the smartLLSM microscope, which uses AI-based instrument control to switch between imaging modes and take high-resolution images of biological specimens. It enables the capture of uncommon or ephemeral biological phenomena at a rate that exceeds human capabilities. Cell [..]

Multi-probe imaging has been shown to accurately image small animal tissue up to several hundred micrometers in size, a technique that could be useful in medical research by allowing researchers to observe tissue microstructure and understand the localization and interaction of multiple molecules, such as cancer cell metastatic lesions. Researchers used a SPECT system with [..]

Researchers have developed a tiny mode-locked laser integrated into a nanophotonic platform capable of producing high-power, ultrafast light pulses. This accomplishment in miniaturizing MLL technology has the potential to increase photonics applications dramatically. Researchers set out to improve a technology that generally requires cumbersome bench-top equipment by shrinking a mode-locked laser (MLL) to the size [..]

Scientists have created a novel method for producing gold nanoparticles (NPs) in tellurite glasses, a type of glass with special qualities utilized in art and adornment for centuries. Gold NPs’ unusual light modulation characteristics have led to applications in various sectors, including colored glass and specific optical components. Tellurite glass is particularly significant for optical, [..]

Computer-generated holography (CGH) is a technology that uses computer algorithms to dynamically reconstruct virtual objects, with applications in various fields such as three-dimensional display, optical information storage and processing, entertainment, and encryption. However, current techniques often rely on projection devices like spatial light modulators (SLMs) and digital micromirror devices (DMDs), which have limited display capabilities. [..]

A research team made an unparalleled advancement in antenna technology by allowing software control of all five fundamental properties of electromagnetic waves. In a world first, the researchers created a universal metasurface antenna that allows for independent and simultaneous modulation of electromagnetic radiation’s amplitude, phase, frequency, polarization, and direction. As research on 6G wireless communication [..]

Researchers have created a novel way for capturing detailed images of things too small to observe with regular microscopes by employing donut laser, i.e., doughnut-shaped light beams. It could aid scientists in better understanding the inner workings of nanoelectronics, such as small semiconductors in computer chips. The study is the most recent advancement in ptychography, [..]

CoreDetector is a new software tool developed by researchers that improves genome-sequencing capabilities, allowing researchers to improve plants through breeding. CoreDetector is built to tackle computationally demanding tasks like matching big and evolutionary varied plant genomes. It uses computer parallelization to perform pairwise sequence alignment between the genomes of population members. The program supports diploid [..]

Subvisible particles (SVPs) are a significant quality attribute of injectable therapeutic proteins (TPs) that must be regulated due to potential medication product quality hazards. The existing compendial methods for analyzing SVPs for lot release give particle size and count information. On the other hand, chemical identification of specific particles is necessary for root-cause analysis. Researchers [..]

Imaging techniques like computed tomography (CT) and positron emission tomography (PET) are now required for identifying and localizing many disorders. According to a newly developed method, PET can now be utilized particularly based on alterations in the human genome. The new genome-based imaging technology, The Imageable Genome, has the potential to aid in the earlier [..]

Metamaterials are artificial nanostructures that affect light and are expensive and difficult to fabricate. A research team created a solution-based 3D-printing method that allows for the low-cost manufacture of metamaterials in desired shapes. By coupling evaporative co-assembly of silica and gold nanoparticles with 3D nanoprinting, the researchers created freeform, freestanding raspberry-like metamolecule (RMM) fibers in [..]

Researchers have revealed groundbreaking research that can potentially alter the field of two-dimensional optoelectronics. Researchers have successfully demonstrated in a groundbreaking study that chicken egg white, i.e., biodegradable albumen, can be a very effective dielectric gate for two-dimensional materials. This breakthrough opens new avenues for sustainable and biodegradable technology in optoelectronic devices. This novel technique [..]

Researchers are enhancing lidar tech for increased versatility, which benefits scientists and explorers in remote sensing, surveying, mapping, 3D-image scanning, hazard detection, and navigation. Lidar, a remote sensing device, employs light pulses to detect distances and object attributes precisely. With continuous investigations, its precision and versatility make it critical for communication, navigation, planetary exploration, and [..]

Researchers have developed a quantum sensing method using a nitrogen-vacancy (NV) center in single nanodiamond sensors, enabling the identification and evaluation of molecules in physiological in situ settings, a crucial goal in biological sciences. This method offers high sensitivity and biocompatibility. However, analyzing the movement of nanodiamonds in real cells reveals that they rotate at [..]

Modern computer models, such as those used in complicated, powerful AI applications, test the limits of classical digital computer operations. New computing architectures that mimic the operating principles of biological neural networks promise quicker, more energy-efficient data processing. A group of researchers has created an event-based architecture that uses photonic processors to transfer and analyze [..]

In medical diagnostics, artificial intelligence (AI) is already widely employed. In a realistic clinical environment, a research team studied how it benefits the diagnosis and management of pigmented skin lesions. The team evaluated the accuracy of two separate algorithms in smartphone applications in diagnosis and therapy suggestions to that of doctors in a study. The [..]

Low-frequency noise, ubiquitous in cities, roadways, and airports, can cause earaches, respiratory impairment, and irritation. Pingpong balls, typically hollow plastic balls, can assist in absorbing this noise, which is difficult to prevent due to its diverse sources and shapes. The researchers describe an acoustic metasurface that uses pingpong balls as Helmholtz resonators to provide low-frequency [..]

Rapid antimicrobial prescriptions are required when viable bacteria are in the blood or bacteremia, which can result in sepsis and bloodstream infection (BSI). Due to the lengthy nature of traditional antimicrobial susceptibility testing (AST), clinicians must rely on experience. In comparison to conventional approaches that take two days, researchers have created a BSI-AST chip for [..]

Because of its significant optical nonlinearity, wide transparency window, and strong electro-optic coefficient, thin-film lithium niobate (TFLN) presents a viable platform for integrated photonics. However, to fully utilize TFLN, additional lasers and photodetectors are necessary. Researchers merged a modified uni-traveling carrier photodiode wafer to improve bandwidth and responsiveness onto a TFLN wafer. LN waveguides and [..]