Single-Cell Genomics By Digital Microfluidics

Single-cell whole-genome sequencing (WGS) is critical for characterizing dynamic intercellular changes in DNA. Current sample preparation technologies for single-cell genomics are complex, expensive, and suffer from high amplification bias and errors. Here, scientists describe Digital-WGS, a sample preparation platform that streamlines high-performance single-cell WGS with automatic processing based on digital microfluidics. Using the method, they [..]