Artificial intelligence (AI) is transforming microscopy by enhancing image efficiency and data analysis. A prominent example is the smartLLSM microscope, which uses AI-based instrument control to switch between imaging modes and take high-resolution images of biological specimens. It enables the capture of uncommon or ephemeral biological phenomena at a rate that exceeds human capabilities. Cell [..]

Multi-probe imaging has been shown to accurately image small animal tissue up to several hundred micrometers in size, a technique that could be useful in medical research by allowing researchers to observe tissue microstructure and understand the localization and interaction of multiple molecules, such as cancer cell metastatic lesions. Researchers used a SPECT system with [..]

A team of scientists has developed a non-invasive handheld biosensor device for detecting biomarkers for Alzheimer’s and Parkinson’s diseases. The results of this biosensor can also be wirelessly transmitted to a laptop or smartphone. The device passed in vitro testing on patient samples, displaying accuracy similar to the most advanced current procedures. Next, this biosensor [..]

By improving digital eye care and eliminating clinical workflow bottlenecks, generative AI and large language models are changing ophthalmology. ChatGPT, a chatbot based on large language models (LLMs) and GPT-3.5 families, has been acclaimed for its capacity to hold human-like conversations and deliver complex answers to various issues. LLM technology has several medical applications, including [..]

Researchers have developed a tiny mode-locked laser integrated into a nanophotonic platform capable of producing high-power, ultrafast light pulses. This accomplishment in miniaturizing MLL technology has the potential to increase photonics applications dramatically. Researchers set out to improve a technology that generally requires cumbersome bench-top equipment by shrinking a mode-locked laser (MLL) to the size [..]

Scientists have created a novel method for producing gold nanoparticles (NPs) in tellurite glasses, a type of glass with special qualities utilized in art and adornment for centuries. Gold NPs’ unusual light modulation characteristics have led to applications in various sectors, including colored glass and specific optical components. Tellurite glass is particularly significant for optical, [..]

Computer-generated holography (CGH) is a technology that uses computer algorithms to dynamically reconstruct virtual objects, with applications in various fields such as three-dimensional display, optical information storage and processing, entertainment, and encryption. However, current techniques often rely on projection devices like spatial light modulators (SLMs) and digital micromirror devices (DMDs), which have limited display capabilities. [..]

Because Helicobacter pylori infection is a considerable risk factor for stomach cancer, regular screening is essential. Endoscopic advancements have helped the removal of big neoplasms; however, finding faint epithelial neoplasms remains difficult. A study found that using LM-NBI (Narrow-Band Imaging At Low Magnification) for comprehensive stomach observation after routine white-light imaging (WLI) was effective, especially [..]

Touchless fingerprint biometrics is a revolutionary innovation that has transformed identity security and made biometric verification more inclusive and accessible. Traditionally, fingerprint scanning was limited to specialized, touch-based hardware, but this method posed challenges such as hygiene risks, bulky hardware requirements, and accessibility limitations. The recent shift to touchless fingerprint biometrics addresses these challenges by [..]

Augmented reality (AR) has become pervasive, blending virtual content with real-world scenes. Waveguide-based AR displays have emerged as a critical technology for wearable AR systems, enabling lightweight, slim form factors and high optical performance. Waveguide combiners, which function as light guides, fold the optical path and replicate luminosity from a small light source across an [..]

Microwave photonics (MWP) has unlocked a new paradigm for Radio Frequency (RF) signal processing using photonic components’ inherent wideband and adjustable nature. Despite numerous efforts to implement integrated MWP filters, a key RF processing functionality, achieving a fully integrated photonic circuit that can merge the megahertz-level spectral resolution required for RF applications with key electro-optic [..]

A research team made an unparalleled advancement in antenna technology by allowing software control of all five fundamental properties of electromagnetic waves. In a world first, the researchers created a universal metasurface antenna that allows for independent and simultaneous modulation of electromagnetic radiation’s amplitude, phase, frequency, polarization, and direction. As research on 6G wireless communication [..]

Researchers have created a novel way for capturing detailed images of things too small to observe with regular microscopes by employing donut laser, i.e., doughnut-shaped light beams. It could aid scientists in better understanding the inner workings of nanoelectronics, such as small semiconductors in computer chips. The study is the most recent advancement in ptychography, [..]

 Lasers are becoming more sophisticated and are being used in an increasing number of medicinal applications. One of the most difficult aspects of employing lasers in surgery is assuring their safety and precision. A team of researchers has created a new device that combines three lasers to cut bone, adjust the cutting depth, and differentiate [..]

CoreDetector is a new software tool developed by researchers that improves genome-sequencing capabilities, allowing researchers to improve plants through breeding. CoreDetector is built to tackle computationally demanding tasks like matching big and evolutionary varied plant genomes. It uses computer parallelization to perform pairwise sequence alignment between the genomes of population members. The program supports diploid [..]

Optoelectronics, which detect or emit light, traditionally rely on thin transistors from graphene and other two-dimensional materials. However, these materials often struggle with band gap opening, leading researchers to explore the Lewis acid treatment method to improve the performance of optoelectronic devices. With its unique physical properties and long-term stability in ambient air, Palladium diselenide [..]

Subvisible particles (SVPs) are a significant quality attribute of injectable therapeutic proteins (TPs) that must be regulated due to potential medication product quality hazards. The existing compendial methods for analyzing SVPs for lot release give particle size and count information. On the other hand, chemical identification of specific particles is necessary for root-cause analysis. Researchers [..]

Imaging techniques like computed tomography (CT) and positron emission tomography (PET) are now required for identifying and localizing many disorders. According to a newly developed method, PET can now be utilized particularly based on alterations in the human genome. The new genome-based imaging technology, The Imageable Genome, has the potential to aid in the earlier [..]

In laser-based manufacturing, a team of researchers has discovered a rapid way to track a surface’s precise location and adjust the focus of an optical system. They employed axial varifocal optics, specifically a TAG lens, which operates at 0.1-1 MHz, avoiding mechanical motion delays in the beam propagation direction. The researchers used dynamic z-scanning for [..]

Researchers have developed a new transmitter using complementary metal-oxide-semiconductor, i.e., CMOS chip technology and silicon photonics, which achieved remarkable data transmission rates while consuming minimal energy. Integrating silicon photonics with electronics is essential for producing practical systems for numerous applications. The combination of the optical modulator and its electronic drive amplifier is a key electronic-photonic [..]