Automated Diagnosis, Segmentation Of CNV In OCT Angiography

January 15th, 2020 | Applications

Accurate identification and segmentation of choroidal neovascularization (CNV) are crucial for detecting and treating exudative age-related macular degeneration. (AMD). Cross-sectional and en-face imaging of CNV is possible with PR-OCTA or projection-resolved optical coherence tomographic i.e., OCT angiography.

Due to the persistence of residual artifacts, CNV segmentation and detection remain challenging even with PR-OCT Angiography. In this article, researchers present a convolutional neural network (CNN)-based algorithm for CNV diagnosis and segmentation.

This research used a clinical dataset that included scans of healthy and diseased eyes scanned with and without CNV. Additionally, no scans were disallowed because of poor image clarity. In testing, 95% specificity and 100% sensitivity allowed for diagnosing all CNV instances from non-CNV controls. The CNV membrane segmentation’s mean intersection over union peaked at 0.88. The suggested algorithm should be advantageous for CNV diagnosis and visualization monitoring because it enables automated categorization and segmentation.

A major factor in vision loss and permanent blindness is age-related macular degeneration (AMD). Due to choroidal neovascularization (CNV), a pathological situation in which new blood vessels develop from the choroid into the outer retina, AMD is classified as neovascular. Because CNV can cause subretinal hemorrhage, lipid exudation, subretinal fluid, intraretinal fluid, or the development of fibrotic lesions, it frequently causes vision loss.

Read more

Related Content: Low-Light Imaging In SWIR With Homodyne Detection

Events & Shows

SPIE Optifab 2024
17 Oct – 19 Oct, 2024
Rochester, New York
Booth 1303

SPIE Photonics West 2025
28 Jan – 30 Jan, 2025
Rochester, New York
Booth 143

The Equal Employment Opportunity Clause required under Executive Order 11246, and the employee notice clause pertaining to employee rights under the National Labor Relations Act, set forth in 29 CFR Part 471 Appendix A to Subpart A, are incorporated by reference in this purchase order. By accepting this purchase order, vendor additionally certifies that, to the extent applicable, this contractor and subcontractor shall abide by the requirements of 41 CFR §§ 60-1.4(a), 60-300.5(a) and 60-741.5(a). These regulations prohibit discrimination against qualified individuals based on their status as protected veterans or individuals with disabilities and prohibit discrimination against all individuals based on their race, color, religion, sex, sexual orientation, gender identity, or national origin. Moreover, these regulations require that covered prime contractors and subcontractors take affirmative action to employ and advance in employment individuals without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status or disability, that it complies with the authorities cited above, and that it does not maintain segregated facilities or permit its employees to perform services at locations where segregated facilities are maintained, as required by 41 CFR 60-1.8.