New Light-sheet Microscopy Technique Allows For Deeper Tissue Imaging

An imaging technique that builds on Bessel beam based light-sheet microscopy and Airy beam based light-sheet microscopy could result in less intrusive and more effective diagnosis for patients. The new method, published in Science Advances, allows light to be shaped so it can reach greater depths within biological tissue, enabling high quality three-dimensional (3D) images to be acquired. It can also allow detailed 3D images of biological specimens to be made without dissection or having to rotate specimens and take multiple images which are then fused together.

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