Light Microscope Can Image Whole Living Organisms at High Resolution

Researchers at the Howard Hughes Medical Institute (HHMI)’s Janelia Research Campus have developed a new light microscope that gives a clearer, more comprehensive view of biological processes as they unfold in living animals. The microscope produces images of entire organisms, such as a zebrafish or fruit fly embryo, with enough resolution in all three dimensions that each cell appears as a distinct structure. What’s more, it does so at speeds fast enough to watch cells move as a developing embryo takes shape and to monitor brain activity as it flashes through neuronal circuits

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