Hybrid Imaging Technique Elucidates Coronary Plaques

Combining optical coherence tomography (OCT) with near-infrared autofluorescence (NIRAF) could enable more accurate identification of coronary artery plaques that are most likely to rupture and cause a heart attack. OCT provides images of tissue microstructure but not of its chemical and molecular composition, said researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH). Now they have combined OCT with NIRAF to create a powerful tool for investigating coronary pathology.

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